Either potassium phosphate or sodium phosphate injection may be used for IV phosphate replacement. The electrolyte content of each of these products is outlined below. The terms phosphate and phosphorus are used interchangeably. Phosphorus is the elemental form and phosphate exists in various ionic forms.
Prescribing and dispensing information. Phosphate Sandoz® contains sodium dihydrogen phosphate anhydrous (anhydrous sodium acid phosphate) 1.936 g, sodium bicarbonate 350 mg, potassium bicarbonate 315 mg, equivalent to phosphorus 500 mg (phosphate 16.1 mmol), sodium 468.8 mg (Na + 20.4 mmol), potassium 123 mg (K + 3.1 mmol);
Efficacy and safety of intravenous phosphate replacement in critically ill patients. Ann Pharmacother 1997 Jun;31(6):683-8. " CONCLUSIONS: The administration of potassium phosphate 15 mmol to critically ill patients with mild-to-moderate hypophosphatemia over 3 hours is both effective and safe.
May 22, 2019· A 24-hour urine phosphate excretion less than 100 mg or a FEPO4 less than 5 percent indicates appropriate low renal phosphate excretion, suggesting that the hypophosphatemia is caused by internal redistribution (eg, refeeding syndrome, acute respiratory alkalosis) or decreased intestinal absorption (eg, chronic antacid therapy, steatorrhea).
IV Phosphate Replacement. Sodium phosphate is preferred for intravenous therapy. Potassium phosphate may also be used if potassium is low. The most reliable method of ordering IV phosphate is by millimoles, then specifying the potassium or sodium salt. • Phosphate replacement must be ordered in mmol of phosphorus.
Phosphorus replacement therapy with sodium phosphates should be guided primarily by the serum inorganic phosphorus levels and the limits imposed by the accompanying sodium (Na+) ion. To avoid hypernatremia or hyperphosphatemia, infuse IV solutions containing sodium phosphates slowly.
Intravenous Phosphate Replacement for Patients NOT receiving Parenteral Nutrition Serum Phosphate Level (mg/dL) mmol of Phosphate 2 to 3 10 mmol < 2 15 mmol Dilute in 150 ml 0.9% NaCl or D5W and infuse over 6 hours. If the patient's potassium is < 3.9, administer as potassium phosphate (contains 3 mmol/mL of phosphate and 4.4 mEq/mL of .
Potassium replacement is primarily indicated when hypokalemia is due to potassium loss, and there is a significant deficit in body potassium. It is also warranted for acute therapy in disorders such as hypokalemic or thyrotoxic periodic paralysis in which the hypokalemia is due to redistribution of potassium into the cells, often in association with significant symptoms.
IV Drug Compatibility Chart A Alteplase (Activase, rTPA) Amiodarone (Cordarone) Argatroban Atropine Calcium chloride Diltiazem (Cardizem) Dobutamine (Dobutrex) Dopamine Epinephrine (Adrenalin) Esmolol (Brevibloc) Furosemide (Lasix) Heparin Insulin (regular) Lidocaine (Xylocaine) Lorazepam (Ativan) Magnesium Sulfate
replacement ~60 meq (~15 meq/hr based on 4h infusion) Always look at potassium level to determine appropriate IV phosphorus product: use K Phos if K < 4.0 mEq/L and Na Phos if K 4.0 mEq/L. For IV replacement: Pharmacy will dilute in 250mL NS or D5W. Infuse over 4-6 hours.
Dietary Potassium (Potassium phosphate) is less effective replacement than KCl Most Hypokalemia is associated with concurrent chloride depletion Oral KCl powder 20 meq in water or juice or KCl tablets
Combined sodium, potassium, chloride, and water depletion may occur, for example, with severe diarrhoea or persistent vomiting; replacement is carried out with sodium chloride intravenous infusion 0.9% and glucose intravenous infusion 5% with potassium as appropriate.
Phosphate Replacement: • Parenteral phosphate preparations often contain significant amounts of potassium ions. • CHECK amount of potassium contained in phosphate replacement solution - Rate of infusion for phosphate replacement will be determined by the amount of potassium in the solution. Consider using a sodium based phosphate .
Phosphate Sandoz ® 1-2 tablets orally three times daily (each tablet contains 16mmol phosphate, 3mmol potassium and 20mmol sodium). Oral replacement is usually sufficient but consider intravenous replacement if patient has phosphate level 0.3-0.5mmol/L and is symptomatic or nil-by-mouth or unlikely to absorb oral phosphate.
A Rapid Intravenous Phosphate Replacement Protocol for Critically Ill Patients C. FRENCH,* R. BELLOMO† *Department of Intensive Care, Western Hospital, Footscray, VICTORIA †Department of Intensive Care, Austin and Repatriation Medical Centre, Heidelberg, VICTORIA ABSTRACT Objective: There is a high incidence of hypophosphataemia in the critically ill.
* IV replacement is with 1 gram magnesium sulfate in 100 ml D5W given over 30 minutes (max rate). PHOSPHATE If K greater than 4.0 mEq/L (Normal range 2.5 - 4.7 mg/dl) Serum Phosphorus Replace with Recheck level less than 1.6 mg/dl. Notify MD 30 mmol NaPO4 IV* 6 hours after replacement
Fluids and Electrolytes INTRODUCTION: The requirements for fluids and electrolytes of the newborn infant are unique. At birth, there is an excess of extra-cellular water (ECW), and this decreases over the first few days after birth. Furthermore, ECW at birth and insensible water loss decrease as birth weight and gestational age increase.
IV Preparations. Potassium Chloride (KCl) 10 meq IV "K bump" Potassium Chloride (KCl) 20 meq use is limited to delivery via Central IV Access; IV Replacement Algorithm. Use 10 meq KCl IV in 50ml solution over 30 minutes minimum. Dextrose containing IV solution not recommended. Risk of Insulin induced exacerbation of Hypokalemia
blue intravenous prescription chart. Out of hours Contact the on-call pharmacist via switchboard. Phosphate replacement in hyperkalaemia, hyperglycaemia and/or fluid restriction For patients with high potassium levels, sodium glycerophosphate is available from Pharmacy. Bags are available in 0.9% sodium chloride on request. Pharmacy are able to
Aug 01, 2018· Potassium Phosphates Injection, USP 3 mM P/mL (millimoles/mL) is a sterile, nonpyrogenic, concentrated solution containing a mixture of mono- and dibasic potassium phosphate in water for injection. The solution is administered after dilution …
• Oral potassium can be prescribed in conjunction with IV potassium. 6,7 • Intravenous potassium should be prescribed in strengths that allow available ready-mixed potassium infusion solutions (prefilled bags) to be used where possible. • Always specify the potassium preparation (Phosphate or …
Oral Phosphate Phosphate SandozÂ® each tablet contains phosphate 16.1mmol, sodium 20.4mmmol, potassium 3.1mmol. Causes diarrhoea. Note high sodium. 4 – 6 tablets daily depending on severity of deficiency. IV Phosphate Phosphate Polyfusor Â® 500ml contains: Phosphate 50mmol (i.e., 1mmol per 10ml) Potassium 9.5mmol; Sodium 81mmol
NOTE: Guidelines generally recommend the use of potassium phosphate for potassium serum concentration less than 4 mg/dL and sodium phosphate for potassium serum concentration more than 4 mg/dL. Potassium phosphate is usually appropriate as most conditions associated with hypophosphatemia are also associated with hypokalemia.
Phosphorus replacement therapy with potassium phosphates should be guided primarily by the serum inorganic phosphorus levels and the limits imposed by the accompanying potassium (K+) ion. To avoid hyperkalemia or hyperphosphatemia, infuse IV solutions containing potassium phosphates slowly
grams.1 Parenteral and oral requirements are, of course, different because intravenous administration bypasses normal digestion and absorption. For IV fluids and PN, the milliequivalent (mEq) is the unit of measurement used for sodium (Na), chloride (Cl), potassium (K), magnesium (Mg), calcium (Ca), and acetate, while the millimole (mM) or the
Phosphate replacement therapy with potassium phosphates should be guided primarily by the serum inorganic phosphate level and the limits imposed by the accompanying potassium (K+) ion. High plasma concentrations of potassium may cause death through cardiac depression, arrhythmias or arrest.
Phosphate Supplement (Oral Route, Parenteral Route) Proper .
Always look at potassium level to determine appropriate IV phosphorus product: use K Phos if K < 4.0 mEq/L and Na Phos if K 4.0 mEq/L. For IV replacement: Pharmacy will dilute in 250mL NS or D5W.
Ensure IV patency. If giving both Mg++ and K+, infuse the Mg++ first. *Intended for intermittent dosing of deficient electrolytes requiring IV replacement. These doses DO NOT reflect recommended daily electrolyte maintenance requirements.
Potassium Dihydrogen Phosphate LH_ICU_Pharmacology_2014_Potassium Dihydrogen Phosphate Page 1 of 5. Drug Guideline Potassium Dihydrogen Phosphate . Summary: This guideline outlines the use of phosphate in intensive care. Phosphate is a major intracellular anion. Total body phosphate in normal adult is about 700g.