sodium sulfide reduction of nitro compounds

Sodium Thiosulfate from the Oxidation of Sodium Sulfides .

Heberlein, and most recently Pearson and Robinson.2. In the field of organic chemistry, especially in the case of aromatic nitro. compounds, the use of sulfide ion as a reducing agent has had wide applica-. tion.

Sodium sulfide | CAS 27610-45-3 | SCBT - Santa Cruz .

Ordering Information. Sodium sulfide sc-251054A 2.5 kg $82.00 Sodium sulfide is a useful sulfur salt for the synthesis of various sulfur compounds, including thiols, thioethers, acyclic suflides, and di- and polysulfides. Sodium sulfide also acts as a reducing agent for aromatic nitro compounds to amines and sulfoxides to sulfides.

Sodium;sulfite | NaO3S- - PubChem

Physical Description. SODIUM SULFITE is a white odorless powder. Density 2.633 g / cm3. Moderately toxic. Sinks in water and dissolves slowly. Also transported as a heptahydrate Na2SO3.7H2O.

Reduction of aromatic nitro compounds to aromatic amines .

Reduction of aromatic nitro compounds to aromatic amines by sodium trimethylsilanethiolate. Jih Ru Hwu; Fung Fuh Wong; Min Jen Shiao

Sodium sulfide - Wikipedia

Sodium sulfide is the chemical compound with the formula Na 2 S, or more commonly its hydrate Na 2 S·9H 2 O. Both are colorless water-soluble salts that give strongly alkaline solutions. When exposed to moist air, Na 2 S and its hydrates emit hydrogen sulfide, which smells like rotten eggs.

Sodium Disulfide - e-EROS Encyclopedia of Reagents for .

They involve reduction of Sulfur with Sodium in liquid ammonia, 4 heating Na with S in a vacuum at 500 °C, 4 or heating Na 2 S 4 with Na in absolute ethanol under inert gas. 4, 5 Na 2 S 2 is formed in situ by heating the aqueous or alcoholic Sodium Sulfide solution with elemental sulfur. 6-9

Reduction of nitro compounds - Wikipedia Republished // WIKI 2

Treatment of aromatic nitro compounds with metal hydrides gives good yields of azo compounds. For example, one could use: Lithium aluminium hydride; Zinc metal with sodium hydroxide. (Excess zinc will reduce the azo group to a hydrazino compound.) Reduction to azoxy compounds. Aromatic compounds are reduced to azoxy compounds by using:

Reduction of aromatic nitro compounds to aromatic amines .

Intensification of Rates and Selectivity Using Tri-liquid versus Bi-liquid Phase Transfer Catalysis: Insight into Reduction of 4-Nitro-o-xylene with Sodium Sulfide. Industrial & Engineering Chemistry Research 2007, 46 (10), 2951-2961.

sodium sulfide reduction of nitro compounds,

Selective reduction of nitro‐heterocycles with sodium .

Nitro‐heterocycles, particularly those containing halogen, were selectively reduced with sodium sulfide in aqueous p‐dioxane to give the corresponding amino‐heterocycles in 70‐89% yields.

sodium sulfide reduction of nitro compounds,

US1765660A - Reduction of aromatic nitro compounds .

A CORPORATI UN 0F DELAW'ARE REDUCTIQN OF ARQMATIC NITRO COMPOUNDS No Drawing. The present invention relates to the reduction of aromatic nitro compounds. It is known that aromatic nitro compounds can be reduced to the corresponding amino compounds by subjecting them to the action of sodium sulfide or a similar agent under suitable conditions.

Reduction of nitro compounds - Wikipedia

Many methods for the production of anilines from aryl nitro compounds exist, such as: Catalytic hydrogenation using: Raney nickel or nickel nanoparticles on zeolite, palladium-on-carbon,. Iron in acidic media (Note: Iron is particularly well suited for this reduction as. Sodium hydrosulfite. .

16.10 Reduction of Aromatic Compounds - Chemistry LibreTexts

Reduction of Nitro Groups and Aryl Ketones Electrophilic nitration and Friedel-Crafts acylation reactions introduce deactivating, meta-directing substituents on an aromatic ring. The attached atoms are in a high oxidation state, and their reduction converts these electron withdrawing functions into electron donating amino and alkyl groups.

Nitro Reduction - Common Conditions

Lithium aluminum hydride reduces aliphatic nitro compounds to amines, but aromatic nitro compounds produce azo products. LiAlH4 is a common reagent for the reduction of nitroalkenes that have been formed using Henry reactions .

THB REDUCTIVE COUPLING OF AROMATIC NITRO …

Reduction of Nitro Compounds to Azoxy Compounds An alkaline mediura has always proven most effective in the re-duction of most nitro compounds to azoxy compounds. Zinin and later Reissert deraonstrated this fact by obtaining yields of up to 90% in the reduction of nitrobenzene and subtituted nitrobenzenes to azoxy

One-step double reduction of aryl nitro and carbonyl .

One-step double reduction of aryl nitro and carbonyl groups using hydrazine, Tetrahedron Letters (2011), doi: 10.1016/j.tetlet.2011.09.112 This is a PDF file of an unedited manuscript that has been accepted for publication.

The Nitro Group in Organic Synthesis - Стр 20

Electrochemically generated nickel is very selective for the reduction of aromatic nitro compounds into anilines, in which alkenyl, alkynyl, halo, cyano, formyl, and benzyloxy groups are not affected. 84 Sodium sulfide has been used for the selective reduction of aromatic nitro group in the presence of aliphatic nitro groups (Eq. 6.44). 85

organic chemistry - Selective nitro reduction of poly .

Selective nitro reduction of poly nitro compounds. Is there any way through which I could selectively reduce one 2 group from a dinitro- or trinitro- compound to an amine. I was reading Solomons and Frhyle and it says that m -dinitrobenzene can be selectively reduced by using 2 …

Reduction Of Nitro Compounds - linkroll

It is also possible to form a nitroaniline by reduction of a dinitroarene using sodium sulfide. Metal hydrides are typically not used to reduce aryl nitro compounds to anilines because they tend to produce azo compounds. (See below) Reduction to hydroxylamines. Several methods for the production of aryl hydroxylamines from aryl nitro compounds .

17.12: Reduction of Aromatic Compounds - Chemistry LibreTexts

Several alternative methods for reducing nitro groups to amines are known. These include zinc or tin in dilute mineral acid, and sodium sulfide in ammonium hydroxide solution. The procedures described above are sufficient for most cases.

Sodium Hydrogen Sulfide - paperplane

[16721-80-5] · HNaS · Sodium Hydrogen Sulfide · (MW 56.07) (hydrate) [140650-84-6] (a nucleophile and reducing agent derived from H 2 S; a reagent for the synthesis of thiols 1 and other divalent sulfur compounds, 2 including thiocarbonyl derivatives; 3 reduces aromatic nitro groups to amines 4 )

Sodium sulfide - Wikipedia

Reagent in organic chemistry. Sodium sulfide reduces 1,3-dinitrobenzene derivatives to the 3-nitroanilines. Aqueous solution of sodium sulfide can be refluxed with nitro carrying azo dyes dissolved in dioxane and ethanol to selectively reduce the nitro groups to amine; while other reducible groups, e.g. azo group, remain intact.

Sodium Hydrosulfite, Sodium Dithionite - organic-chemistry

Sodium Hydrosulfite, Sodium Dithionite Sodium hydrosulfite (sodium dithionite, Na 2 S 2 O 4 ) is an inexpensive and safe reducing agent, which for example enables the reduction of aromatic nitro and diazonium compounds to anilines.

Sodium Sulfide - paperplane

Sodium sulfide and polysulfides are better reducing agents than H 2 S and have been widely used in the reduction of aromatic nitro groups to amino groups (the Zinin reaction). 5,6c,f,7c,34 The reduction can be selective for one nitro group of several. In the reduction shown in eq 16, Na 2 S reduces the o-nitro group whereas Tin(II) Chloride reduces the p-nitro group. 34a The Zinin reaction is especially …

Selective reduction of aromatic / aliphatic nitro groups .

Sodium sulfide can be used to reduce selectively aromatic / aliphatic nitro groups. In the absence of water, the aromatic nitro group can be reduced selectively in the presence of a secondary aliphatic one. However, in the presence of a tertiary aliphatic nitro group, the reduction is accompanied by 50% of the styrene derivative 6.

Sodium Hydrosulfite, Sodium Dithionite - organic-chemistry

Sodium Hydrosulfite, Sodium Dithionite Sodium hydrosulfite (sodium dithionite, Na 2 S 2 O 4 ) is an inexpensive and safe reducing agent, which for example enables the reduction of aromatic nitro and diazonium compounds to anilines.

Reduction of nitro compounds - enwikiademic

Aromatic nitro compounds. The reduction of aryl nitro compounds can be finely tuned to obtain a different products typically in high yields. Reduction to anilines. Many methods for the production of anilines from aryl nitro compounds exist, such as: Catalytic hydrogenation using palladium-on-carbon, [11] platinum(IV) oxide, or Raney nickel [12]

Amine synthesis by nitro compound reduction

Categories: N-H Bond Formation > Reduction of nitro compounds. Recent Literature. The combination HSiCl 3 and a tertiary amine enables a mild, metal-free reduction of both aromatic and aliphatic nitro groups to amines. The reaction is of wide general applicability and tolerates many functional groups.

Sodium Thiosulfate from the Oxidation of Sodium Sulfides .

In the field of organic chemistry, especially in the case of aromatic nitro compounds, the use of sulfide ion as a reducing agent has had wide applica- tion. This phase of the subject has been studied by Zinin, Beilstein and Kurbatow, Lobry de Bruyn and Blanksma, Brand, Vesely, J. B. Cohen and Fliir~cheim.~

Reduction of nitro compounds - partnersademic

Aromatic nitro compounds. The reduction of aryl nitro compounds can be finely tuned to obtain a different products typically in high yields. Reduction to anilines. Many methods for the production of anilines from aryl nitro compounds exist, such as: Catalytic hydrogenation using palladium-on-carbon, [11] platinum(IV) oxide, or Raney nickel [12]

Sodium Sulfide - Dittmer - - Major Reference Works - Wiley .

Sodium Sulfide † Other versions of this article . 4 reduces aromatic nitro compounds to amines 5) Physical Data: mp ∼50 °C (hydrate, loses most of its water below 100 °C); mp 1180 ± 10 °C (pure Na 2 S); d 1.43 g cm −3 (anhydrous 1.86 g cm −3); E 0 (S 2 .